Revolutionising Diagnostics Whole Exome Sequencing with DNBSEQ
Unleashing the Power of Genomic Sequencing: MGI's DNBSEQ™ Technology Revolution
Dr. Weilin Liu talks about the dynamic field of genomic sequencing, MGI’s DNBSEQ™ technology stands as a ground-breaking innovation, redefining efficiency, accuracy, and versatility in genetic research. This cutting-edge technology, integrated with MGI’s advanced sequencing platforms and reagents, is revolutionizing genomic studies and research applications.
DNBSEQ™ Technology: A Milestone in Genomic Accuracy
MGI's DNBSEQ™ technology transforms single-stranded circular DNA into unique DNA nanoballs (DNBs) via rolling circle replication. This innovative approach ensures high signal intensity and unmatched sequencing precision.
Reduced Errors
Controlled enzymatic reactions during replication substantially minimize amplification errors compared to PCR-based methods.
No Index Hopping
A critical advantage of DNBSEQ™ is the near-elimination of index hopping, enhancing sample identification accuracy.
SNP/Indel Sensitivity
Delivers heightened accuracy and sensitivity in detecting single nucleotide polymorphisms and small insertions/deletions.
DNBSEQ™ T7: Ultra-Fast Performance
The powerhouse of MGI's ecosystem, designed for rapid, large-scale data production without compromising quality.
Rapid Sequencing
Completes a PE100 run in just 22 hours, making it one of the fastest high-throughput instruments globally.
Flexible Operation
Run 1 to 4 flow cells independently and simultaneously with a user-friendly touchscreen interface.
Massive Throughput
Generates 1 to 4 terabases per day, with a single flow cell producing up to 5,000 million reads.
DNBSEQ™ G400
Versatile Output
Offers a flexible range of 75 to 720 Gb per run, making it ideal for both research and clinical labs.
Dual Flow Cell Efficiency
Processes dual flow cell runs in as little as 16 hours, providing efficient turnaround for routine workflows.
Platform Flexibility
Universal Integration
Compatible with various library prep kits; the Library Conversion Kit ensures seamless migration to MGI platforms.
Chemistry Update
Please note: Hot MPS sequencing reagents are no longer available in the current product lineup.
Pioneering Genomic Research with DNBSEQ™
MGI’s combination of DNBSEQ™ technology and sequencing platforms marks a significant advancement in genomic research. Catering to diverse research needs, from whole-genome sequencing to transcriptomics and single-cell studies, MGI’s solutions offer unmatched efficiency and precision. Researchers and institutions are invited to explore and adopt these innovative technologies in their genomic research, collaborating with MGI for further innovation and discovery.
Disclaimer: The information provided in this blog is for educational and informational purposes only and is not intended for use in diagnostic procedures. MGI products mentioned are for research use only.
Published 2 Feb 2021
