The Department of Pathology at Tan Tock Seng Hospital (TTSH) has installed an automated Massively Parallel Sequencing (MPS) workflow from MGI. The system includes the MGI SP-100 automated library preparation system, the MGI DNBSEQ-G50RS* MPS platform and the MegaBOLT bioinformatics analysis accelerator.
The sequencing platform combines MGI’s DNA Nanoball (DNB) technology with cPAS sequencing chemistry to deliver improved sensitivity and accuracy, reduced duplication rates and low PCR bias.
The TTSH Department of Pathology is currently validating the analytical performance of the workflow. Once fully implemented, the system will support the department’s work in precision oncology and molecular pathology, helping clinicians and researchers generate high-quality genomic data for clinical and translational applications.
Laboratory installation
The installation represents an important step in expanding advanced sequencing capabilities within the hospital’s pathology laboratory and supporting the growing demand for genomic testing in clinical practice.
Note
All sequencers and sequencing reagents are not available in Germany, the United States and Spain.




