Microbial Whole Genome Sequencing Package
MGI’s solution combines automated sample prep with CycloneSEQ long-read and DNBSEQ short-read sequencing for precise whole genome assembly and targeted resistance profiling. It supports direct-from-sample analysis without culture, delivering rapid detection of drug resistance mutations, MTBC typing, and evolutionary tracing. Powered by MTB-Explorer software, it offers WHO-based mutation annotation and automated reporting for reliable, actionable insights.
Product Parameters & Specs
| Parameter | DNBSEQ Solution | CycloneSEQ Solution |
|---|---|---|
| Sample Type | Isolate and culture microbial samples (bacteria, fungi, viruses, etc.) | Isolate and culture microbial samples (bacteria, fungi, viruses, etc.) |
| Recommended DNA Input | 1 ng – 200 ng | 500 ng |
| Automatic Library Preparation | SP-100 / D4 | SP-100 / CyclonePrep-4 |
| Library Preparation Time | 3 hours | Manual / sample: 40 min SP-100 (8 samples): 1.5 h SP-100 (16 samples): 1.8 h SP-100 (24 samples): 2.3 h CyclonePrep-4 / sample: 1.5 h CyclonePrep-4 (8 samples): 3 h |
| Sequencing Platform | E25, G99, G500 | CycloneSEQ-WT02 |
| Read Length | PE100 | Not applicable (long-read sequencing) |
| Bioinformatics Analysis Software | MGAP, BFI | MGA |
Performance & Data Output
| Parameter | DNBSEQ Solution | CycloneSEQ Solution |
|---|---|---|
| Recommended Analysis Data Volume | 5M reads per sample | ≥ 50× sequencing depth per sample |
| Detection Type | SNV, INDEL | SNV, INDEL |
| Solution Advantages | Cost-effective | Real-time sequencing with more complete and continuous genome assembly |
Workflow & Compatibility
| Parameter | DNBSEQ Solution | CycloneSEQ Solution |
|---|---|---|
| Server Compatibility | PFI / PFI Pro / G99ARS | PFI / PFI Pro / CycloneSEQ-WT02 Workstation |
Key Features
Comprehensive Genome Coverage
- Combines long-read and short-read sequencing to deliver complete, accurate genome assemblies—even in complex regions.
Direct-from-Sample Testing
- No culture required—sequence DNA directly from sputum or lavage fluid for faster results.
Automated Sample Prep
- Streamlined library preparation with minimal hands-on time, boosting lab efficiency and consistency.
Advanced Resistance Profiling
- Detects 13,000+ drug resistance mutations based on WHO catalogs for precise drug resistance prediction.
Robust Bioinformatics
- MTB-Explorer software automates mutation annotation, strain typing, and evolutionary tracing with reliable reports.
Rapid Turnaround
- Optimized workflows and real-time sequencing enable faster insights to support timely clinical and research decisions.
Discover More
Get in Touch
Phone
📞(+86) 4000-688-114
Marketing & PR
MGI_Branding@mgi-tech.com
Careers
MGI_Recruiting@mgi-tech.com
Investor Relations
MGI_IR@mgi-tech.com
